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- Objective To construct a multivalent DNA vaccine. 目的构建日本血吸虫多价DNA疫苗。
- Objective To construct a multivalent DNA vaccine encoding Ag85A,ESAT-6 and CFP-10 antigens from Mycobacterium tuberculosis,and to preliminarily study its immunogenicity. 目的构建包含结核杆菌3种抗原蛋白Ag85A、ESAT-6和CFP-10真核表达质粒的多价DNA疫苗,并对其在小鼠体内的免疫原性进行初步分析。
- Our work offers a new approach to improve the immune response by multivalent DNA vaccine, if the vaccine DNAs are properly combined. 这些结果表明:不同DNA疫苗的适当组合有可能在获得多价疫苗的同时,提高DNA疫苗的免疫效果。
- Conclusions The multivalent DNA vaccine of P. falciparum could induce specific immune reactions,which might have provided some new experimental data for the further research of malaria vaccines. 结论恶性疟复合多价DNA疫苗可诱发特异的免疫应答,为疟疾DNA疫苗的研究提供了一定的理论及实验依据。
- Construction of multivalent DNA vaccine of Schistosoma japonicum and its identification 日本血吸虫多价DNA疫苗的构建及鉴定
- Keywords Schistosoma japonicum;GST;fatty binding protein;multivalent DNA vaccine; 日本血吸虫;GST;脂肪酸结合蛋白;多价DNA疫苗;
- Multivalent DNA vaccine 多价DNA疫苗
- The use of DNA vaccine for the induction of mucosal immunity are reviewed. 现主要就DNA疫苗的黏膜免疫进展作一综述。
- CONSTRUCTION AND IMMUNE RESPONSE OF A DNA VACCINE VECTOR?EXPRESSING HEAT SHOCK PROTEIN 70 OF ?LEISHMANIA DONOVANI? 杜氏利什曼原虫热休克蛋白70的DNA疫苗表达载体构建及体内应答研究
- This paper summarized the research advance in the live attenuated vaccine,sporozoite vaccine and DNA vaccine. 综述了减毒活疫苗、子孢子疫苗和核酸疫苗的研究进展。
- To construct a therapeutic HBV DNA vaccine and investigate its expression in mammalian cells. 摘要目的构建一种治疗性的乙肝DNA疫苗并测定它的表达。
- This article summarizes the present research tatus and applied prospects in tuberculosis DNA vaccine. 本文概述了结核病DNA疫苗研究的现状及其应用前景。
- DNA vaccine can induce potent humoral and celluar immune respondses in numerous animals. DNA做为一种新型的疫苗在免疫人和动物后可以引起强烈的体液免疫和细胞免疫。
- Therefore,pTL-8/AMA-l(rtTA) combined with pUHS6-l is a good regulable DNA vaccine candidate against Plasmodium falciparum. pTL一8/AMA一1(rtTA)附加 pUHS6一构成了可调控的DNA免疫系统。
- Both CpG motifs and pIL-2 have positive effects on the production of the antibody in mice post-injected CEA DNA vaccine. CpG基序和IL - 2表达质粒对DNA疫苗产生抗体有促进作用
- This article summarizes vaccine construction、principle、adjuvant、inoculability、safety, present problem and prospect of DNA vaccine applications. 就DNA疫苗的构建、作用原理、佐剂、接种方法、安全性、目前存在的问题及应用前景作一综述。
- The present researches have pointed out that HBV DNA Vaccine will become a new vaccine to prevent and treat Hepatitis B in the future. 目前研究认为,乙型肝炎DNA疫苗很可能成为预防和治疗乙型肝炎的全新一代疫苗。
- They found three doses of DNA vaccine given by tattooing produced at least 16 times higher antibody levels than three intramuscular injections. 他们发现3种剂量DNA疫苗,通过纹身产生的抗体水平比普通的肌肉注射至少高16倍。
- Methods:We constructed Mycobacterium tuberculosis MPT64 antigen DNA vaccine(pM)and ubiquitin-MPT64 fusion gene DNA vaccine(pUM). 目的:用遍在蛋白质调节结核杆菌单一抗原DNA疫苗,以期获得更强的免疫保护。
- Based on the previous research, we furthered the research on the anti-pancreatic cancer effect of the DNA vaccine MUC1-VNTR in vivo and in vitro. 材料和方法: 小鼠胰腺癌细胞系panc02由美国MD Anderson Cancer center赠送,表达全长MUC1的质粒pcDNA3-MUC1由美国匹兹堡大学Dr.