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- Keywords Multidrug resistance 1( mdr 1);Cochlea;Lateral wall;Extrusive traffic; 关键词多药耐药基因1;耳蜗;外侧壁;外向运输;
- Keywords Aminopeptidase N, myelo-specific promoter;multidrug resistance 1 gene;manganese superoxide dismutase gene;retrovirus;hepatoma cell;myeloid cell; 氨肽酶N;骨髓特异性启动子;锰超氧化物歧化酶基因;多药耐药基因;逆转录病毒载体;骨髓细胞;肝癌细胞;
- multidrug resistance 1 gene 多药耐药基因1
- Multidrug resistance 1 多药耐药基因-1
- Objective To evaluate the expressions of multidrug resistance associated protein (MRP 1) and vascular endothelial growth factor (VEGF) in acute leukemia and their clinical significance. 目的探讨儿童急性白血病患者多药耐药相关蛋白1(MRP1)与血管内皮生长因子(VEGF)的表达及其临床意义。
- BACKGROUND & OBJECTIVE: Multidrug resistance is one of the main caus es of treatment failure of chemotherapy. 背景及目的:耐药性产生是化疗失败的主要原因之一,克服耐药性的方法之一是使用逆转剂。
- Expression of multidrug resistance gene in patients with maligant trophoblastic tumor and its clinical significance. 多药耐药基因在滋养细胞肿瘤组织中的表达及其临床意义。
- Objective To elucidate the multidrug resistance(MDR) in bladdertransitional cell carcinoma. 目的研究膀胱移行细胞癌的多药耐药性。
- However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment. 对瘤组织而言,多药耐药是化疗失败的主要原因。
- The multidrug resistance rate of positive-integron isolates is far greater than the negative ones. 整合子阳性菌株对多种抗生素的耐药率远大于整合子阴性菌;
- The investigate of distribution of integron in multidrug resistance isolates in Jiaozhou Bay was carried out. 摘要为调查整合子在胶州湾水域多重耐药菌中的分布情况。
- The mechanism of bacterial efflux pumps is one of the important factors resulting in bacterial multidrug resistance. 细菌耐药性,尤其是多重耐药问题日益严重,给临床治疗带来极大的困难。
- However,the multidrug resistance (MDR) of nasopharyngeal carcinoma is the key role in the failure of the treatment. 而多药耐药(MDR)机制是导致其化疗等综合治疗失败的主要原因。
- Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure. 临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药(MDR)。
- Conclusions The multidrug resistance (MDR) in endometrial carcinoma may be related with the expression of MDR1 gene. 结论子宫内膜癌对化疗的耐药可能是一种固有性MDR,这可能与MDR1基因的表达有关。
- Objective To study the relationship between p16,bcl 2 expression and multidrug resistance (MDR) in adenocarcinoma of colon. 目的 研究大肠腺癌p16、bcl-2 表达与多药耐药性的关系。
- Objective To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in MCF7/ADR and its mechanism. 目的:研究屈洛昔芬(DRO)对乳腺癌耐药细胞株(MCF7/ADR)多药耐药性(MDR)的影响。
- Objective: To study the correlation of multidrug resistance protein P170 and active T cell in acute myeloblatlic leukemia(AML). 研究目的:探讨急性髓性白血病耐药蛋白P_(170)与活化T细胞的关系。
- The relative quantities of GCS and mdr1 genes in multidrug resistance group were significantly increased compared with non-resistance group(P < 0.001). 急性白血病耐药组标本的GCS基因及mdr1基因的扩增条带吸光度(A)相对比值均明显高于非耐药组(P<0.;001)。
- Human bladder transitional cell cancer BIU 87 cells and multidrug resistant BIU 87/ADM cells were treated with daunorubicin (DNR) combined with JSB 1 and CsA alone or together and with JSB 1 and verapamil(Ver) alone or together. 为了证实抗P?糖蛋白(P?gp)单克隆抗体协同环孢素A(CsA)逆转人膀胱癌耐药细胞亚株的抗药性以及建立能有效地克服MDR的治疗方案,对人膀胱移行细胞癌BIU?87细胞系和BIU?87/ADM耐药细胞亚株经柔红霉素(DNR)与抗P?gp单克隆抗体JSB?1和单独或联合CsA;