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- Multidrug resistance moderator 耐药调节剂
- BACKGROUND & OBJECTIVE: Multidrug resistance is one of the main caus es of treatment failure of chemotherapy. 背景及目的:耐药性产生是化疗失败的主要原因之一,克服耐药性的方法之一是使用逆转剂。
- Expression of multidrug resistance gene in patients with maligant trophoblastic tumor and its clinical significance. 多药耐药基因在滋养细胞肿瘤组织中的表达及其临床意义。
- Objective To elucidate the multidrug resistance(MDR) in bladdertransitional cell carcinoma. 目的研究膀胱移行细胞癌的多药耐药性。
- However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment. 对瘤组织而言,多药耐药是化疗失败的主要原因。
- The multidrug resistance rate of positive-integron isolates is far greater than the negative ones. 整合子阳性菌株对多种抗生素的耐药率远大于整合子阴性菌；
- The investigate of distribution of integron in multidrug resistance isolates in Jiaozhou Bay was carried out. 摘要为调查整合子在胶州湾水域多重耐药菌中的分布情况。
- The mechanism of bacterial efflux pumps is one of the important factors resulting in bacterial multidrug resistance. 细菌耐药性,尤其是多重耐药问题日益严重,给临床治疗带来极大的困难。
- However,the multidrug resistance (MDR) of nasopharyngeal carcinoma is the key role in the failure of the treatment. 而多药耐药(MDR)机制是导致其化疗等综合治疗失败的主要原因。
- Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure. 临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药(MDR)。
- Conclusions The multidrug resistance (MDR) in endometrial carcinoma may be related with the expression of MDR1 gene. 结论子宫内膜癌对化疗的耐药可能是一种固有性MDR,这可能与MDR1基因的表达有关。
- Objective To study the relationship between p16,bcl 2 expression and multidrug resistance (MDR) in adenocarcinoma of colon. 目的 研究大肠腺癌p16、bcl－2 表达与多药耐药性的关系。
- Objective To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in MCF7/ADR and its mechanism. 目的:研究屈洛昔芬(DRO)对乳腺癌耐药细胞株(MCF7/ADR)多药耐药性(MDR)的影响。
- Objective: To study the correlation of multidrug resistance protein P170 and active T cell in acute myeloblatlic leukemia(AML). 研究目的：探讨急性髓性白血病耐药蛋白P_(170)与活化T细胞的关系。
- The relative quantities of GCS and mdr1 genes in multidrug resistance group were significantly increased compared with non-resistance group(P < 0.001). 急性白血病耐药组标本的GCS基因及mdr1基因的扩增条带吸光度(A)相对比值均明显高于非耐药组(P<0.;001)。
- The overexpression of membrane proteins functioning as drug efflux pumps is one of the main mechanisms for multidrug resistance of Candida albicans. 膜转运蛋白高表达导致多药抗药是白念珠菌抗药性产生的最重要机制之一。
- The tumor embryonic associated antigen CDH, tumor multidrug resistance associated N-GSLs CMH and neoplasm inhi-bitor globoside were found. 发现了肿瘤胚胎相关抗原CDH、肿瘤耐药相关中性鞘糖脂CMH和肿瘤抑制因子Globoside ;
- Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely. 肿瘤多药耐药(MDR)是近年来肿瘤治疗研究的困扰之一,其产生机制非常错综复杂。
- The reversion of multidrug resistance in tumor cell line MCF-7/Adr by ribozyme [ J ].Natl Med J Chin, 1997, 77(7): 494-6. Ribozyme基因对人肿瘤细胞株MCF-7/Adr多药抗药性的靶向逆转[J].;中华医学杂志;1997;77(7):494-6
- Clone and DNA sequencing were used to analyze the resistance-related gene cassettes. 50% of multidrug resistance isolates were detected with integron. 研究发现，胶州湾多抗性细菌污染严重50%25的多重耐药菌携带整合子；
