Mono-,di- or tri-substituted DHT intermediates were synthesized by the Michael addition of DHT orDADHT with methyl acrylate, then reacted with different alcohols or phenol to obtain carboxyethyl- 2,4-dioxohexahydro-1,3,5-triazine derivatives.

• 六氢-1,3,5-三嗪-2,4-二酮(DHT)和1,3-二乙酰基-六氢-1,3,5-三嗪-2,4-二酮分别与丙烯酸甲酯的迈克尔加成反应合成一、二或三取代六氢-1,3,5-三嗪-2,4-二酮中间体,再与不同的醇或酚反应合成了羧乙基-DHT衍生物。