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- Molecule targeted drug 分子靶向药物
- This article review recent advances of lung cancer biotherapy and biochemotherapy,including molecule targeted therapy and gene modified dendritic cell therapy. 本文对近年来肺癌的生物治疗(包括分子靶向治疗、基因修饰树突状细胞治疗)和生物化疗的研究进展进行了综述。
- The biotherapy of lung cancer developed quickly,especially the molecule targeted therapy,which had achieved graveness progression and the curative effect was striking. 肺癌的生物治疗发展迅速,尤其是肺癌的分子靶向治疗,已取得了重大进展,疗效显著。
- Polysaccharides, pectin, dextran, guar gum and chitosan have been used or tested for targeted drug delivery in pharmaceutical applications. 多聚糖如海藻酸盐、胶质、右旋糖苷、凝胶已在制药应用中用于或正试验用于药物的靶向传输。
- Biodegradable macromolecule carried controlled drug releasing and biodegradable macromolecule carried targeted drug delivery are the focus of recent investigation in macromolecular medicine. 生物可降解型高分子载体控制释放药物和生物可降解型高分子载体靶向药物是近年来高分子药物研究的重点。
- Targeted drug delivery system (TDDS) is a hot issue in Pharmaceutics After long time pursuing, people become to realize the targeted mechanism, property, biodistribution and pharmacokinetics of TDDS. 卵巢癌是女性常见的肿瘤之一,极大地危害了女性的健康,目前治疗手段不甚理想,因此设计一种能将药物靶向于卵巢癌细胞的给药系统更具有实际意义。
- This review presents the related factors of the metastsis of lung cancer and the related new targeted drugs. 本文就肺癌转移的各个参与因素以及相关的新靶向药物的临床研究作一综述。
- Biological Therapy and Molecule Targeted Therapy of Cancer 肿瘤的生物治疗与分子靶向治疗
- Now that there are several targeted biotech drugs on the market, researchers are starting to test whether two targeted drugs are better than one. 既然市场上有很多靶向生物技术药物,那么研究者正开始试验两个靶向药物是否会比一个更好些。
- Survival of advanced CRCs has achieved more than 24 months with the use of new chemotherapeutic agents, especially when combining with molecular targeted drugs. 与此同时,新的治疗方法和药物也在不断问世,分子靶向药物是发展最快的一个方向,特别是单克隆抗体与传统的化疗药物的联合已经使得晚期大肠癌患者的生存期超过了24个月。
- AIM To develop an orally administered colon targeting drug delivery system dexamethasone succinate dextran (DSD) tablets. 目的研制口服结肠定位释放药物的地塞米松葡聚糖酯及其片剂。
- The concentration of DSP was measured by HPLC, and used to calculate the relative targeting drug delivery index(DDI) of DSP. 分别给大鼠口服各种DSP制剂,测定经时血药浓度和结肠组织中分布量,计算药物的相对靶向释药指数(DDI)。
- A new targeting drug delivery liposome of berberine hydrochloride was prepared by the method of thin-film evaporation method. 采用薄膜蒸发发制备了一种新的具有生物靶向性的盐酸小檗碱脂质体。
- Pharmaco-pathology is a novel branch in clinical pathology, whose main work is identifying molecular targets on tumor tissues by pathological methods and supplying evidence for targeted drug therapy. 药物病理学是临床病理学领域的新兴分支学科,其主要工作是利用病理学手段识别肿瘤组织存在的分子靶点,为临床针对性靶向治疗提供用药依据。
- Sulfadiazine-polylactide,a tumor targeting drug carrier,was successfully synthesized by the phase transfer catalysis(PTC)with tetrabutyl ammonium chloride hydroxide as catalyst. 采用相转移催化法以四丁基氯化铵为催化剂合成了端基含磺胺嘧啶的聚乳酸,将肿瘤导向基团引入了可生物降解药物载体。
- The company has targeted a profit for the year. 公司已经规定了今年的利润指标。
- Keywords targeted drug delivery;sulfadiazine;fluorour acil; 导向药物;磺胺嘧啶;氟尿嘧啶;
- Moreover, non-cytotoxic agents such as small molecules targeting receptor tyrosine kinases and intracellular signaling pathways have been used in the clinical field. 替莫唑胺及亚硝基脲类药物耐药性得到了部分解决以及非细胞毒性药物如酪氨酸激酶抑制剂及细胞间信号传导通路抑制剂在临床中的应用。
- Moreover, aurora kinases also function in tumorigenesis.Some small molecules targeting to aurora kinases were found to have significant roles in tumor inhibition. 此外,极光激酶还参与了肿瘤形成的过程,已经发现一些靶向作用于极光的小分子具有显著的抑癌作用。
- Major Interests : Novel techniques in molecular diagnostics in genetics diseases, cancer, and serious infectious diseases.Also include nanomaterials in immunoassays and targeting drug delivery. 研究兴趣 :分子诊断(遗传病,肿瘤,重大传染病等),生物纳米材料在免疫诊断及药物靶向输送的应用。