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- Survival of advanced CRCs has achieved more than 24 months with the use of new chemotherapeutic agents, especially when combining with molecular targeted drugs. 与此同时,新的治疗方法和药物也在不断问世,分子靶向药物是发展最快的一个方向,特别是单克隆抗体与传统的化疗药物的联合已经使得晚期大肠癌患者的生存期超过了24个月。
- The efficacy of CDA-II is based on its molecular targeting ability.Molecular targeting drugs that target tumor genes are the highlight of the new anti-cancer drugs development. CDA-II的有效性也建立在它对分子靶点的选择性,癌基因分子靶点药物是目前开发抗癌新药的热门。
- Pharmaco-pathology is a novel branch in clinical pathology, whose main work is identifying molecular targets on tumor tissues by pathological methods and supplying evidence for targeted drug therapy. 药物病理学是临床病理学领域的新兴分支学科,其主要工作是利用病理学手段识别肿瘤组织存在的分子靶点,为临床针对性靶向治疗提供用药依据。
- Keywords molecular targeted drug gefitinib treatment;research progress; 分子靶向药物吉非替尼;治疗;研究进展;
- Molecular targeted drugs 分子靶向药物
- molecular target drug 分子靶向药物
- So MAPK can serves as a molecular target for diseases treatment. 因此,MAPK是潜在的治疗分子靶。
- The relationship between pharmacogenetics and drug therapy(including treatment outcome and toxicity),and molecular target therapy of cancer are discussed in this review. 该文主要对药物遗传学与肿瘤药物治疗(包括药物治疗结果与毒副反应)、分子靶向治疗的关系进行综述。
- It is a potential molecular target for tumor-selective drug delivery,including delivery of radiolabeled folate-chelate conjugates for diagnostic imaging. 在肿瘤靶向药物输运体系中,包括输运放射性核素标记的叶酸螯合物显像剂,叶酸受体是一种潜在的分子靶。
- This review presents the related factors of the metastsis of lung cancer and the related new targeted drugs. 本文就肺癌转移的各个参与因素以及相关的新靶向药物的临床研究作一综述。
- Molecular Targeting Drug 分子靶向药物
- The molecular targeted agent, cetuximab and bevacizumab, combined with chemotherapy, would be more promising therapeutic regimens in the treatment of advanced gastric caner. 而将西妥昔单抗和贝伐单抗等分子靶向药物与化疗合用,有望成为更具前景的治疗方案。
- Now that there are several targeted biotech drugs on the market, researchers are starting to test whether two targeted drugs are better than one. 既然市场上有很多靶向生物技术药物,那么研究者正开始试验两个靶向药物是否会比一个更好些。
- The recent discovery of several genes whose malfunctioning leads to Alzheimer's provides the pharmaceutical industry with important molecular targets for drug development. 最近发现的几种导致早老性痴呆症的有缺陷基因给制药业提供了重要信息以找出针对这些细胞靶的有效药物。
- The SL approach may sensitize the malignant cell to drugs aimed at secondary molecular targets. SL治疗法可以驱使恶性肿瘤细胞对次级靶位点的蛋白敏感。
- Polysaccharides, pectin, dextran, guar gum and chitosan have been used or tested for targeted drug delivery in pharmaceutical applications. 多聚糖如海藻酸盐、胶质、右旋糖苷、凝胶已在制药应用中用于或正试验用于药物的靶向传输。
- Monoclonal antibody (McAb) was highly specific to its antigen and could be made for specific molecular target sites. 苯并二吡咯类抗生素有极强的细胞毒性,抗肿瘤活性强;
- For each molecular target, such as cocaine, a corresponding aptamer can be selected from a large DNA library. 对于一个分子靶标(如可卡因)来说,可以从DNA库中选出相对应的核酸适体。
- Bevacizumab and other antiangiogenic drugs are likely to play a key role in the treatment of malignant glioma, as are combinations of molecularly targeted compounds. 新的制剂如贝伐单抗等抗血管新生的药物可能是最新的方向。
- The researchers expect to find some specific markers at the molecular level, which is used to diagnosis and offer effective information and resources for molecular targeted therapy. 科研人员期望从分子水平上找到对前列腺癌诊断具有特异性的标记物并对分子靶向治疗提供有效的信息和资源。