Moclobelide was synthesized from ethanolamine by nucleophilic substitution and Schotten-Baumann reaction,followed by condensation with anoverall yield of 71.2%.

• 以乙醇胺为起始原料；经亲核取代、肖特一鲍曼反应和缩合反应制得吗氯贝胺；总收率可达71.；2%25。