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- WT1 is related to the prognosis of AML and uses as a marker in detecting the minimal residual disease. 认为WT1基因和急性髓细胞白血病(AML)的预后有关,可以作为微小残留病检测的标记;
- Therefore, WT1 gene is a new prognostic factor and a new marker for the detection of minimal residual disease in AL. WT1基因是一个有用的预后指标与检测微小残留病的标记。
- Monitoring the bcr/abl fusion gene by RT-nested-PCR can be used to evalute the efficacy of the therapy and detect the minimal residual disease(MRD). RT -nestedPCR方法检测bcr/abl融合基因可以作为临床诊断、判定预后的指标 ,适用于微小残留病变的监测
- Conclusion Monitoring of the WT1 gene by Nest RTPCR would be a surely marker for the detection of minimal residual disease (MRD) in acute leukemia. 结论 用Nest、RT-PCR测定WT1基因的表达可作为检测白血病微小残留病(MRD)的一项指标。
- Still, small volume or minimal residual disease has been recogenized as a potentially suitable target for radiolabeled antibodies.RIT... 虽然如此,放射性核素标记的抗体在治疗微小病灶中的应用前景看好。
- Objective To improve the clinical significance of detecting minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL). 目的为提高急性淋巴细胞白血病(ALL)微小残留检测的临床意义。
- The quantitative assessment of WT1 expression in peripheral blood samples by FQ-RT-PCR may be a useful tool for monitoring minimal residual disease. 对外周血WT1基因表达进行定量分析,可用于微小残留病的监测。
- Objectives To investigate the clinical significance of AML1/ETO fusion mRNA in diagnosing and monitoring of minimal residual disease and its prognostic value. 目的 研究AML1/ETO融合mRNA在儿童急性髓性白血病M2型中的表达及其对残留白血病监测及预后的指导意义。
- Minimal residual disease (MRD) as a marker of antileukemic drug efficacy is being used to assess risk status and, in some cases, to adjust the intensity of therapy. MRD作为抗白血病药物疗效标志,被用于评估患者危险,在某些病例中也用于调整治疗强度。
- Minimal residual disease (MRD) is defined that there are residual leukemia cells in the range of 10~6-10~8 in the patients who are in complete remission (CR). 患者经治疗后,达到临床和血液学的完全缓解,体内仍有106-108个残留白血病细胞,称为微小残留病(minimal residual disease, MRD)。
- Objective To explore the clinical significance of quantitative analysis of minimal residual disease (MRD) cells DNA in children with acute lymphoblastic leukemia (ALL). 目的探讨定量监测儿童急性淋巴细胞白血病(ALL)微量残留病(MRD)细胞DNA变化的临床意义。
- Objective To discuss the significance of minimal residual disease detection in acute B-lymphoblastic leukemia, Surface differentiation antigen CD45- leukemic cells were detected. 目的探讨细胞表面分化抗原45阴性(CD45-)白血病细胞在急性B细胞性白血病微小残存病变监测中的意义。
- There was high level expression of CD 117 in acute promyelocytic leukemia. Minimal residual disease of APL can be detected using multi-color flow cytometry to analyze the expression of CD 117 , CD 34 and HLA-DR. 提示 :APL患者有较高水平的CD117表达 ,CD117与CD34 、HLA DR联合进行多色流式细胞术分析 ,可用于APL微小残留病灶的检测。
- More and more attention has been paid to the function of cellular immunotherapy in eradicating minimal residual disease of acute leukemia and extending the remission stage after therapy. 细胞免疫治疗在消除白血病微小残留病和延长治疗后缓解期方面的作用正日益受到人们的重视。
- It can help clinical doctors judge the disease transformation by detecting the minimal residual disease and tuomor symbol gene.It also have incommensurable function for basic knowledge researchers. 在检测微小残留病变,肿瘤标志性基因及病毒负荷量等方面为临床医生判断病情,了解预后发挥着不可替代的作用。
- Objective:Evaluation of methylation specific polymerase chain reaction and its potential clinical value in the detection of minimal residual disease (MRD) in adult acute leukemia with P15. 目的:评价由甲基化特异性聚合酶链反应分析P15基因甲基化对成人急性白血病微小残留病灶的检测价值。
- Objectives To investigate the possibility of predicting the outcome in children with B lineage acute lymphocytic leukemia(ALL)by monitoring minimal residual disease(MRD)in bone marrow. 目的探讨儿童B系急性淋巴细胞白血病(B-ALL)患儿骨髓微小残留病(MRD)及检测,预测预后的可能性。方法应用四色荧光抗体标记法通过流式细胞仪检测儿童B-ALL的MRD。
- Objective To explore the significance of bcr/abl fusion gene in the diagnosis and the minimal residue disease monitoring CML. 目的探讨bcr/abl融合基因检测在诊断慢性粒细胞性白血病(CML)和监测CML残留病灶中的意义。
- As steady heredity polymorphism, single nucleotide polymorphism is becoming the focus of attention in monitoring chimerism and minimal residual diseas... 本文就单核苷酸多态性的遗传特性,分析技术,在造血干细胞移植和其它方面的应用进行了综述。
- and evaluate its clinical value in the minimal residual disease(MRD). 探讨定量检测CML微小残留病变(minimal residual disease,MRD)的临床意义。