Micromentic characteristics of gra nules and dissolution of tablets were determined utilizing uniform design method.The experimental data were treated by multivariate regression program.

• 测定了颗粒的粉体学性质及压制片的释放度，采用多元逐步回归程序进行数据处理，从得到的回归方程系数可确定处方及工艺因素对颗粒性质及片剂释放度的影响。