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- Methoxy Camptothecin 甲氧基喜树碱
- Methoxy 1 groups are split off with boiling HI and converted to ?? 甲氧基用沸腾的碘氢酸分解,使甲氧基脱落并转为甲基碘。
- An equatorial methoxy group was completely inert to the Grignard reagent. 位于平伏键的甲氧基,则没有这种可能,因而不发生反应。
- Effects of Camptothecin, Amsacrine and Vinblastine on the cell cycle of lymphocytic or myelogenous leukemia cells. 喜树碱、胺苯吖啶、长春花碱对淋巴细胞性和髓样白血病细胞周期的影响。
- Topotecan(TPT)is a semisynthetic analogue of the natural product camptothecin that exerts antineoplastic activity. Topotecan(TPT)是类似天然抗癌药物喜树碱的半合成新药。
- R" is a replaceable function, e. g. acetoxy, methoxy, their acyloxy and alkoxy homologs or halo. R”是取化基,如乙氧基、甲氧基及它们的环氧和烷氧同系物或卤基。
- Objective To review some delivery systems for camptothecin and its analogs in recent years. 目的对喜树碱类药物的一些特殊传递系统进行综述。
- R " is a replaceable function, e. g. acetoxy, methoxy, their acyloxy and alkoxy homologs or halo. 是取化基,如乙氧基、甲氧基及它们的环氧和烷氧同系物或卤基。
- At present,our main products are 10-Hydroxy camptothecin,7-Ethyl-10-Hydroxy camptothecin,cefotiam,eplerenone and so on. 目前,公司产品主要有10-羟基喜树碱、7-乙基-10-羟基喜树碱、头孢替安、依普利酮等产品。
- Preparation of 10-hydroxy camptothecin (HPT) by camptothecin (CPT) through oxidation and photoactivation was studied. 文中采用半合成法对10羟基喜树碱的制备进行了研究,以喜树碱为原料,通过氧化和光化两步反应得到HPT初产品。
- The electric effects of methoxy in ortho-position differ from that in meso-position. 甲氧基处于氨基的邻位的电子效应和处于间位时不同。
- This paper summarized the synthesis and antitumor activity of camptothecin and its derivatives in recent years. 该文总结了近年来喜树碱及其衍生物的合成与活性研究方面的最新进展。
- Methoxy polyethylene glycol(MPEG), which grafted with cellulose diacetate(CDA), was applied as a modifier. 采用聚乙二醇单甲醚(MPEG)作为改性剂,与二醋酸纤维素(CDA)进行接枝反应。
- In conclusion, the methoxy in benzene is the very key factor of affinity for the D2 receptor. 推断苯环上R6位甲氧基对苯酰胺类化合物与多巴胺D2受体亲合性起关键性作用。
- Conclusion Two modified form of synergy can effectively solve the poor solubility of camptothecin and the mot... 结论两种修饰方式的协同作用可以有效的解决天然喜树碱溶解性差,母体毒副作用大的缺点。
- The concentration of camptothecin was determined in different tissues of Camptotheca acuminata seedling. 摘要测定不同生长期喜树苗各器官中喜树碱的含量。
- Method Liposome, polymer carrier, microsphere and other delivery systems for camptothecin were reviewed in detail. 目的对喜树碱类药物的一些特殊传递系统进行综述。
- This papar summarized modifying molecular structure and relation between structure to activity of camptothecin. 本文对结构修饰和构效关系做一简要综述。
- This article deals with the synthesis of 3 methoxy 4 hydromandelic acid by condensation of guaiacol and glyoxalic acid in akaline condition. 本文研究了在碱性条件下,由愈创木酚和乙醛酸合成3-甲氧基-4-羟基扁桃酸的反应。
- The accumulation of camptothecin and 10-hydrocamptothecin presented evident relativity in the different growth stages. 在生长过程中,喜树叶片中喜树碱和10-羟基喜树碱的含量变化呈现出明显的相关性。