Methods:To set up the control group that has 35 cases of healthy adults and treatment group that has 45 patients with CRF. The levels of plasma endothelin (ET-1), D-Dimer(DDi), BUN and Scr were investigated before and after treatment by sodium ferulate.

• 方法 :应用常规治疗加注射用阿魏酸钠治疗慢性肾衰竭非透析患者 4 5例 ,观察治疗前后血浆ET - 1、DDi及血肌酐 (Scr)、尿素氮 (BUN)改变 ,并与 2 1例常规治疗组、35例健康对照组相比较。