Methods:Guinea pigs were used to test the dermatic acute toxicology,dermatic long-term toxicology,and the allergic reaction of CDPDFM by various experiments.

• 方法:采用复方颠倒散药物面膜对豚鼠进行皮肤急性毒理、长期毒理及变态反应试验,观察其体重变化、皮肤以及各脏器的反应;对家兔进行皮肤刺激试验,观察其皮肤反应。