Methods: to choose ten MDR related genes: BAX, Bcl-2, BCRP, FAS, GST-ji, LRP, MDR1, MGMT and MRP, and their expressions in SHI-1 and SHI-1/AS2 were tested by RQ-PCR.

• 结果:SHI-1/AS2细胞对于As_2O_3耐药性为SHI-1的2.；2倍；形态学上SHI-1/AS2保持了同SHI-1相同的特征。