Methods: Total of 65 SD closed colony strain rats as well as Wistar strain rats were used in this experiment. Kidney transplantation was performed from SD to Wistar strain(allogeneic)according to procedure of Fabre with some modification.

• 方法：封闭SD和Wistar大鼠各65只，肾移植采用改进的Fabre法，SD大鼠肾移植给Wistar为同种异体移植(allografts)，根据给药的不同分五组。