Methods: To establish model of normobaric hypoxia in mice with isoprenaline; determinated the coronary blood flow of isolated guinea pig heart and rabbits platelet aggregation induced by ADP in vitro.

• 方法:采用小鼠常压耐心肌缺氧模型,豚鼠离体心脏冠脉流量及体外抗血小板聚集等药效学试验。