Methods: Palonosetron was prepared from 1-naphthalenecarboxylic acid and 4-carbethoxypiperidine via a series of steps such as amination,cyclization,hydrolysis,dehydration,reduction,etc.

• 方法:以1萘-甲酸和4哌-啶甲酸乙酯为原料经胺化、成环、水解、胺化、脱水、关环、还原等反应合成目标物。