Methods When E7.75d,mice of the control group and the ganoderma spores group were given intragastrically onetime retinoic acid all-trans.

• 方法于实验对照组和灵芝孢子组小鼠孕期胚胎(E)7.；75d时一次性胃饲全反式维甲酸；造成这两组孕鼠的胚胎出现神经管畸形。 然后；给予灵芝孢子组孕鼠胃饲灵芝孢子溶液。