Methods There were 1.6 cases with thyroid goiter, 2 males and 14 females, we aspriated cells from their thyroid, put it on a piece of glass, stain with HE and observe the changes of cytologic morphology in microscopy.

• 方法甲状腺肿大患儿16例，男2例，女14例，用细针吸取甲状腺组织，放在玻片上经特殊染色后，于光学显微镜下观察细胞形态学的改变。