Methods The serum YMDD mutation,HBV DNA,ALT and HbeAg levels of 60 patients on lamivudine therapy were detected by FQ-PCR,ELISA,and rate method,respectively.

• 方法采用实时荧光定量PCR、ELISA及速率法分别检测60例乙肝患者经拉米呋啶治疗后其血清YMDD、HBV DNA、乙肝标志物及ALT的变化情况。