Methods The product was synthesized from 1-(4-nitrophenyl)piperazine by Boc protection,reduction of nitro group,acylation,hydrazinolysis and cyclization.

• 方法以1-(4-硝基苯基)哌嗪为起始原料,经Boc保护、硝基还原、酰化、肼解、环合制得目标化合物。