Methods The osteoblasts MC3T3-E1 were cultured in vitro with 10-6 mol/L XW630 containing culture medium,while estrogen and tetracycline were used as control drugs in the medium.

• 研究表明，成骨细胞含有特异性的雌激素受体，雌激素可以直接作用于成骨细胞[1，2]。