Methods Starting with 3-fluorophenyl isocyanate and(R)-epichlorohydrin,linezolid was synthesized through cyclization,substitution,acylation,bromination,and condensation.

• 方法以(R)环氧氯丙烷和间氟苯基异氰酸酯为起始原料,经环化、叠氮化、还原、酰化、溴代、缩合反应得到利奈唑酮。