Methods Rats were subjected to OME by injecting lipopolysaccharide (LPS) into middle ear cavity, and animals were divided into LPS group and BPI group.

• 方法 :采用大鼠中耳腔注射脂多糖 (L ipopolysaccharide,L PS)制备 OME模型 ,动物分为 L PS实验组和 BPI治疗组。