Methods It is estimated the effect after treated two cycles; the chemotherapy plans was 5 fluorouracil (320 mg.m 2/d, 8 hours continuously, 2 weeks) and small doseage cisplatin (5 mg/m 2/d, 5 times per week, 2 weeks), having 2 weeks for rest.

• 方法 FP方案 5 -氟尿嘧啶 32 0 mg·m2 - 1 · d- 1 ,持续 8h,连用 2周 ,DDP5 mg·m2 - 1 · d- 1每周 5日连用 2周 ,其后休息 2周 ,连用两个周期后进性疗效评价。