Methods Dimethoate at dose of 0, 12.5, 25 and 50mg/kg was daily given by gavage to SD rats for 28 days and to SHR for 14 days.

• 方法：以0mg/kg，12.；5mg/kg，25mg/kg和50mg/kg乐果灌胃染毒，每天一次，连续28天染毒SD大鼠，以同样剂量连续14天染毒SHR。