Methods 5 severe patients who treated with Cefoperazone suffered in intestinal flora alteration, 4 cases with candida albicans ans, 1 with Welch s basillus.

• 方法5例重症患者经使用头孢哌酮后出现肠道菌群失调,粪培养4例为白色念珠菌,1例梭状芽孢杆菌。