Method: Zolmitriptan was synthesized from L-pheneylalanine via nitration,esterfication,reduction(-COOR),cylization,-NO_2 reduction,diazotization,diazonium salt reduction and fischer indole synthesis.

 
  • 方法:以(L)-苯丙氨酸为原料,经硝化,酯化,还原(酯基),环合,还原(硝基),重氮化,还原(重氮盐)和费歇尔吲哚合成共八步反应制得佐米曲普坦。
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