Method: Diclofenac sodium was used as model, and azone and l-menthol and synthetic borneol and olieic acid and essential oil from Cnidium monnieri were used as transdermal enhancers.

 
  • 方法:以双氯芬酸钠为模型药物,以氮酮、薄荷醇、冰片、油酸、蛇床子挥发油为促透剂,在离体透皮吸收实验装置上进行透皮吸收试验,计算累积透过量、渗透速率、稳态流量和滞后时间,运用灰关联聚类法评价促透效果。
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