Method Canrenone was synthesized from dehydroepiandrosterone by oxidation,enol etherification,oxirane formation,cyclocondensation,decarboxylation and dehydrogenation.

• 方法以去氢表雄酮为起始原料,经过氧化、烯醇醚化、环氧化、环缩合、脱羧和脱氢等6步反应合成坎利酮。