Method AAV?TH and AAV?AADC were stereotaxically co?injected into the denervated striatum of Parkinsonian rat; apomorphine?induced rotational behavior and the immunohistochemistry of TH and AADC were analysed.

• 方法应用腺伴随病毒（AAV）载体共转导酪氨酸羟化酶（TH）和芳香族氨基酸脱羧酶（AADC）基因于模型大鼠纹状体，以复合感染方式将AAV?TH和AAV?AADC通过立体定向法注射入帕金森病大鼠病损侧纹状体，连续观测转导后大鼠行为改善情况，并以免疫组化方法测定TH和AADC表达。