Median surial at the end of treatment was 30.2 months in patients with eleated leels. This point was not reached in patients with normalized leels.

• 在治疗结束时，蛋白酶体水平升高患者的中位生存期是30.；2个月。蛋白酶体水平恢复正常的患者没有观察到终点事件。