MSCs could survive in normal host myocardium for at least 12 weeks. Some of transplanted cells expressed titin and the assembled titin could be detected in the cells adjacent to host myocardium.

 
  • MSCs植入正常心肌组织后能存活至12周,部分移植细胞表达titin,且与宿主心肌细胞相邻的细胞表达titin组装程度更高,随时间延长表达逐渐明显,其后进入平台期,但细胞体积及胞浆发育均不及正常心肌细胞;
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