METHODS:Twelve eight-week-old SHR was randomized into distilled water group(SHR_ DW group,n=6)and atorvastatin-treated group(SHR_ ATV group,n=6). The age-matched Wistar-Kyoto rats(WKY)were used as control(WKY group,n=6).

• 方法:12只8周龄的SHR随机分为蒸馏水饲养组(SHRDW组,n=6)与阿托伐他汀治疗组(SHRATV组,n=6),并以6只同周龄的正常血压大鼠(WKY)作为对照(WKY组,n=6)。