METHODS: Using the method of polymerase chain reaction single strand conformation polymorphism (PCR-SSCP), the point mutation of the ABCB4 gene exon 6 and exon 14 in 31 women with ICP were detected.

• 方法：采用聚合酶链反应单链构象多态性(PCR-SSCP)方法对31例妊娠期肝内胆汁淤积症患者进行ABCB4基因外显子6和外显子14的点突变筛查。