METHODS Using HPLC to determine the FA in the static diffusion cell device at defferent time, we calculated the transdermal permeability coefficient (PC) and the accumulative percutaneous absorption rate (APAR) of the FA .

• 方法 采用静态扩散装置,用HPLC测定扩散池中不同时间阿魏酸的含量,计算其渗透系数和累积透皮吸收百分率。