METHODS The in vitro dissolubility of 2 kinds of metformin hydrochloride tablets was determined by basket method and the dissolution parameters were analyzed with variance analysis method.

• 方法采用转篮法对两种盐酸二甲双胍进行溶出度测定并用片剂四用仪测定其他指标,并进行溶出参数的方差分析。