METHODS The antibody levels elicited by microsphere formulations in mice for 1 year were examined, the anamnestic responses to a low dose booster 1 year after priming were also examined.

• 方法观察破伤风类毒素聚乳酸微球免疫动物后1年中,动物血清抗体反应及免疫记忆反应的规律。