METHODS Liquid chromatography-tandem mass spectrometry (LC-MSn) was used for the separation and analysis of SIPI and its metabolites in rats urine, feces and bile after an intravenous dose of SIPI.

• 方法采用液相色谱-质谱(LC-MSn)联用技术,检测在单剂量静脉注射给予SIPI后大鼠尿,粪及胆汁中的SIPI及代谢物。