METHOD:The enhancing rate(ER) of dicaine hydrochloride with different voltage through rat skin were determined respectively using valia-chien two-chamber diffusion cells.

• 方法：以盐酸丁卡因为模型药物，采用去毛大鼠腹部皮肤和双室扩散池，分别测定不同电压下的增渗倍数(ER)。