Long-term glucocorticoid therapy promptly induces osteoporosis, whose severity depends on the dose and duration of the treatment, and there is no safety threshold for adverse effects on bone.

• 长期的糖皮质激素治疗可以迅速导致骨质疏松,其严重性依赖于剂量和治疗时间,它引起的骨副作用并没有安全的界限。