Long-term excessive iodine intake resulted in an increased TT_4 level and a decreased TT_3 level in maternal serum,meanwhile,hepatic and renal type 1 deiodinase activity decreased dose-dependently.

• 长期过量碘摄入可使母鼠血清TT_4显著升高,TT_3显著降低,肝、肾1型脱碘酶活性呈剂量依赖性的降低。