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Lipoprotein lipase geae 脂蛋白脂酶基因
Abstract： Lipoprotein lipase(LPL)plays a rate-limiting role in triglyceride-rich lipoprotein metabolism. 摘要：脂蛋白脂肪酶(LPL)是脂蛋白代谢中甘油三酯分解的主要限速酶.
Aim: To study the polymorphism of lipoprotein lipase(LPL)gene exon 9 in Chinese combined hyperlipidemia(CHL). 目的:研究中国人混合型高脂血症患者脂蛋白脂酶基因多态性。
The effect of hypoxia training to triglyceride and lipoprotein lipase in rats ...... 低氧训练；脂代谢；三酰甘油；脂蛋白脂肪酶
In our experiments, the time for incubating serum and the first reagent which was short of lipoprotein lipase was extended. 尽管反应系统中不存在脂蛋白脂酶，但随着样品和反应系统预孵育时间的延长，再加入脂蛋白脂酶后，甘油三酯的测定值逐渐下降。
The content of triglycerides determinated after the second reagent (lipoprotein lipase) was added decreased with the time for incubation extended. 说明现有酶法测定系统不能扣除血清中游离甘油对甘油三酯测定的影响。
The activities of lipoprotein lipase(LPL)and lecithin-cholesterol acyltrans-ferase (LCAT) were examined before and after treatment. 用单盲法进行临床观察和检测患者治疗前后脂蛋白脂酶(LPL)、卵磷脂胆固醇酰基转移酶(LCAT)的活性。
The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity. (脂蛋白脂酶3，端非翻译区：单倍体结构及与后肝素血浆脂酶活性的相关性。
Methods:Changes in fasting plasma triglyceride levels, hepatic triglyceride secretion and clearance rate, insulin and lipoprotein lipase were observed in VMH lesioned normal rats. 方法：应用高胰岛素血症的下丘脑腹内侧核损伤性肥胖大鼠和正常胰岛素水平的SD大鼠，饲以高脂肪、蔗糖和正常饲料，观察甘油三酯的代谢、胰岛素、脂蛋白脂酶活性的变化，分析胰岛素与甘油三酯生成、脂蛋白脂酶活性的相关关系。
CLA may inhibit the enzymes,lipoprotein lipase(LPL),stearoyl-CoA desaturase(SCD),fatty acid synthase(FAS)and so on,which are related to lipid metabolism. 抑制脂肪代谢相关酶脂蛋白脂酶、硬脂酰辅酶A脱氢酶、脂肪酸合成酶等的活性来产生降脂作用。
The pathogenesis of this disease is not altogether clear, but it clearly involves in genetic variation of lipoprotein lipase（LPL）, a key enzyme in lipid metabolism. 过去曾有研究指出当人体内脂蛋白脂解酶基因发生变异时，易导致血液中三酸甘油酯浓度增加，进而造成高三酸甘油酯血症。
To investigate the molecular mechanism of IMF deposition, we explored the expression patterns of lipoprotein lipase (LPL) gene, hormone sensitive lipase (HSL) gene and the polymorphism of LPL gene. 本课题运用分子生物学技术对LPL和HSL基因的表达和基因多态性两方面进行研究,为进一步揭示肌内脂肪沉积的遗传机制奠定基础。
A heterozygous mutation of lipoprotein lipase (LPL) (Pro207Leu) was identified in a 17-year-old girl with hyperchylomicronemia by PCR-SSCP and DNA sequencing. This mutation reduces the LPL catalytic activity and results in hyperchylomicronemia. 以PCR SSCP和DNA测序确定 1例 17岁女孩的脂蛋白脂酶 (LPL)基因为杂合子突变(Pro2 0 7Leu) ,此突变降低了LPL的催化活性和引起高乳糜微粒血症
Lipoprotein lipase gene plays a pivotal role in the atherosclerotic process.Understanding the potential mechanisms may help improve the strategies-making and develop new specific therapies. 脂蛋白脂酶通过影响血脂代谢等途径在冠心病发生、发展中起着重要作用。充分认识有关机理可以提高冠心病及合并脂质代谢异常的干预和策略制定的水平。
Objective To identify the role of lipoprotein lipase (LPL) in lipid metabolism through the dynamic observation of lipid levels in lipoprotein lipase gene knockout heterozygous mice (LPL+/-mice). 摘要目的通过脂蛋白脂肪酶(LPL)基因敲除杂合子LPL(+/-)小鼠模型脂质代谢的动态观察，进一步明确LPL在脂代谢中的关键作用。
familial lipoprotein lipase deficiency 家族性脂蛋白脂(肪)酶缺乏症, 家族性高脂蛋白血症i型和v型, 家族性脂蛋白脂酶缺乏症
adipose tissue lipoprotein lipase activity 脂肪组织脂蛋白脂酶活性
lipoprotein lipase deficiency, familial 家族性脂蛋白脂(肪)酶缺乏症, 家族性高脂蛋白血症I型和V型
skeletal muscle lipoprotein lipase activity 骨骼肌脂蛋白脂酶活性
Keywords diabetes mellitus;type 2;lipoprotein lipase;triglyceride; 糖尿病;2型;脂蛋白脂酶;甘油三酯类;