Leonuine was synthesized from syringic acid by acetylation,reaction with SOCl_ 2,Gabriel reaction et al,total yield is 18.95%.

• 本文中以丁香酸为原料；用醋酐进行乙酰化、酰氯化、盖布瑞尔等六步反应得到益母草碱；总收率为18.；95%25。