Large protein conformational changes accompany DNA deformation, creating a bipartite catalytic site that positions the DNA backbone near a reactive tyrosine and a coordinated magnesium ion.

• 大型蛋白构象变化，伴随脱氧核糖核酸变形，造成偶催化站点位置脱氧核糖核酸骨干近被动酪氨酸和协调一致的镁离子。