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- Objective Entecavir(ETV) was superior to lamivudine(LMV) in achieving histologic improvement,ALT normalization and HBV DNA suppression at week 48 in phase III trials. 目的III期临床研究结果显示恩替卡韦(ETV)治疗48周,在组织学改善、ALT复常和HBVDNA抑制方面均优于拉米夫定(LMV);
- Methods The serum YMDD mutation,HBV DNA,ALT and HbeAg levels of 60 patients on lamivudine therapy were detected by FQ-PCR,ELISA,and rate method,respectively. 方法采用实时荧光定量PCR、ELISA及速率法分别检测60例乙肝患者经拉米呋啶治疗后其血清YMDD、HBV DNA、乙肝标志物及ALT的变化情况。
- In studies that compared entecavir with lamivudine, entecavir was more effective in reducing HBV DNA levels, even when ALT levels were only slightly elevated. 在与拉米夫定的对照研究中，嗯替卡韦减低DNA水平更有效，甚至当ALT仅有轻微的升高。
- Higher baseline ALT,lower baseline HBV DNA levels and the HBeAg decline more than 50% at the early stage of treatment(with EVR) are significant predictors of HBeAg seroconversion for Lamivudine treatment. 治疗前,较高的ALT水平、较低的HBVDNA定量值及出现早期病毒应答是影响拉米夫定治疗慢性乙肝疗效的主要因素。
- The age and the diagnosis of the disease before lamivudine therapy, the liver function, HBsAg, HBsAb，HBeAg，HBeAb，HBcAb, HBV DNA load, the rate of YMDD mutation and pre-C mutation were also recorded. 按病情加重后的诊断分为肝功能衰竭组和慢性乙型肝炎组进行比较。
- They were divided by HBsAg and HBV DNA into 4 groups. 按血清HBsAg及乙肝病毒脱氧核糖核酸(HBV DNA)检测结果分组。
- Objective:To study the relationship between HBV M and HBV DNA. 目的:研究乙肝病毒血清学标志物(HBV M)与乙肝病毒脱氧核糖核酸(HBV DNA)之间的关系。
- A COMPARATAREL STUDY OF PCR FOR HBV DNA AND ELISA FOR HBV MARKERS. PCR法检测食品从业人员血清中的HBV-DNA与ELISA法检测结果比较
- HBV DNA was observed both in the cytoplasm and nuclei of hepatocytes. HBVDNA可见于受染肝细胞的胞核或胞浆内，而HDVRNA绝大部分见于肝细胞胞核。
- Relationship of HBV DNA and serum HBV marks in patients with hepatitis B. 水平与血清标志物的关系。
- The relationship between the amount of HBV DNA in serum and HBV markers. 乙型肝炎病毒DNA含量与血清标志物的关系。
- Analysis of correlation among HBV DNA, HBV preS1 antigen and HBV markers. 乙肝病毒DNA和前S1抗原及其标记物三者相关性分析
- LHBs of 171 CHB patients were not statistically different from HBV DNA(P>0.05). 171份乙肝患者HBV DNA、LHBs的检测结果显示:LHBs的检测结果与HBV DNA的检出结果差异无统计学意义(P>0.;05)。
- Results The positive rate of HBVDNA was 56.7%,and the level of HBV DNA was 4.16+0.57(LogE,copies/ml)in saliva. 结果60例慢性HBV 感染者中唾液HBV DNA 阳性34例;平均HBV DNA 含量为4.;16±0
- Quantitative detection of serum HBV DNA is useful in assessment of liver damage and guidance in antivirus therapy. 定量检测HBVDNA对判断肝损害程度、指导抗病毒治疗有重要意义
- The percent age of HBV DNA(+)in patients with both eAg (-) and eAb(+) was 26.13%. eAg(-)同时eAb(+)者中HBVDNA(+)占26.;13%25。
- The positive patients for HBV DNA and in china HCV antibody were 75.0% and 38.5% respectively. 我们采用聚合酶链反应技术和ELISA法检测了52例原发性肝细胞癌患者血清乙型肝炎病毒脱氧核糖核酸（HBVDNA）及抗丙型肝炎病毒（HCV），阳性率分别为75.;0%25，38
- The relationship between AFP and ALT, AST and HBV DNA was analyzed by correlation analysis. 采用相关分析法分析AFP与血清丙氨酸转氨酶 (ALT)和血清门冬氨酸转氨酶 (AST)以及AFP与HBVDNA之间的关系。
- In 42 cases recovery model group(RMG) samples,4 cases were HBV DNA positive with a positive rate of 9 52%. 恢复期模式组有42例;但仍可检出HBVDNA4例;阳性率为9.;52%25;
- The serum HBV DNA become undetectable(<300 copies/ml by PCR)in 76% of ETV group versus 43% of LVD group(P<0.0001). 用PCR法;ETV组中有76%25的患者测不到病毒(<300拷贝/ml);而LVD组中仅为43%25。
