LN-SCA,MFD41,D18S47,D2S123,D3S1317 and D13S158. PCR was performed in a total volume of 25 l in 70 cases (examined group; 25 cases of UC,7 cases of UC with dysplasia, 8 cases of UCACRC. control group:30 cases of SCRC). MSI was detected by PCR - SSCP.

• 应用聚合酶链式反应一单链构像多态性方法(PCR一SSCP)检测溃疡性结肠炎、溃疡性结肠炎伴不典型增生及溃疡性结肠炎相关性大肠癌组织中的微卫星状态(6个位点:LNSCA、MDF41、D18弘7、D25123、D3S1317、 D13S158)。