Keywords thienorphine;thienorphine glucuronide;analgesia;metabolite;distribution;excretion;Pharmacokinetics;LC-MS/MS;whole-body autoradiography;isotopic tracer method;

• 噻吩诺啡;噻吩诺啡葡萄糖醛酸结合物;镇痛活性;代谢转化;分布;排泄;药代动力学;LC-MS／MS;整体放射自显影;同位素示踪技术;