Keywords rehmannia glutinosa;achyranthis;radix;orthogonal experiment;high performance liquid chromatogram;maximally tolerated dose;alloxan;animal model;diabetes mellitus;pharmacodynamics;

• 地黄;牛膝;正交试验法;高效液相色谱;最大耐受量;四氧嘧啶;动物模型;糖尿病;药效学;