Keywords Escherichia coli;succinic acid;metabolic engineering;pyruvate carboxylase;formate dehydrohylase;glyoxylate shunt;gene knock out;

• 大肠杆菌;琥珀酸;代谢工程;丙酮酸羧化酶;甲酸脱氢酶;乙醛酸循环;基因敲除;