Keywords Benproperine;Metabolism;Chem-synthesis;Microbial transformation;Liquid chromatography-mass spectrometry;Pharmacokinetics;Stereoselectivity;Chiral drug;Antitussive;

• 苯丙哌林;药物代谢;化学合成;微生物转化;液相色谱质谱联用技术;药物动力学;立体选择性;手性药物;镇咳;